Opportunity Information: Apply for RFA CK 22 005

The Vector-Borne Disease Regional Centers of Excellence funding opportunity (RFA CK 22 005) is a CDC cooperative agreement program designed to boost the United States' ability to respond to the rising burden of vector-borne diseases by establishing and supporting regional Centers of Excellence. The idea is to build durable, regionally grounded hubs that can develop practical tools and strategies for controlling arthropod vectors (such as mosquitoes, ticks, fleas, and other biting or disease-carrying insects and arachnids) and reducing transmission of the pathogens they spread, while also strengthening the workforce and partnerships needed to put those tools into real-world practice.

At the core of the program is applied research focused on actionable prevention and control. Funded centers are expected to study and test approaches that either prevent vector bites or suppress populations of vectors that matter most in their region, along with the human disease agents those vectors carry in the environment. This emphasis on "applied" work signals that the CDC is looking for research that can translate into operational guidance, evaluated interventions, and field-ready methods, rather than purely theoretical or laboratory-only studies. The centers are meant to produce evidence that public health agencies and vector control programs can use to make decisions and improve outcomes.

A second major objective is workforce development, specifically training the next generation of public health entomologists who can serve as subject matter experts at state and local levels. The NOFO explicitly ties this training goal to hands-on participation in the applied research agenda by involving graduate students and postdoctoral fellows directly in center projects. In practice, this means the centers are expected to function as training environments where early-career scientists gain experience in surveillance, vector control evaluation, field and laboratory methods, and the practical realities of working with public health partners and community stakeholders.

The third objective centers on strengthening linkages between academia and practice. The program is structured to encourage sustained collaboration among universities and the public health ecosystem, including state, territorial, tribal, and local public health organizations, vector management programs, and other relevant stakeholder groups as needed. The intent is to improve the development, evaluation, and implementation of vector and vector-borne pathogen suppression strategies by ensuring that researchers and practitioners are working together, sharing information, and aligning research questions with on-the-ground needs. Alongside these partnerships, the NOFO highlights "communities of practice" as a way to support knowledge exchange and coordination, but frames them as supporting elements that should ultimately enhance the applied research outcomes rather than replace them.

Administratively, this is a discretionary federal grant issued as a cooperative agreement, meaning the CDC typically expects to have substantial involvement in the project in areas like coordination, technical input, or shared planning compared to a standard grant. The opportunity is housed under the Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), and is associated with CFDA 93.084, which relates to public health programs.

Eligibility is broad and includes various levels of government (state, county, city/township, and special district governments), public and state-controlled institutions of higher education, independent school districts, federally recognized tribal governments, tribal organizations, public housing authorities/Indian housing authorities, and nonprofit organizations both with and without 501(c)(3) status (excluding higher education institutions in those nonprofit categories). The listing also notes an "Others" category with additional eligibility clarification referenced in the full announcement, which typically signals that some additional entity types may qualify depending on the CDC's specific criteria.

In terms of funding scale, the award ceiling is listed as up to $2,000,000, with an expectation of about 10 awards, suggesting a multi-center national network with substantial resources per region. The notice was created on October 14, 2021, with an original application deadline of January 18, 2022, and electronic submissions due by 5:00 pm Eastern Time on the deadline date. Overall, the opportunity is structured to create regionally focused centers that deliver practical vector control research, train specialized public health entomology talent, and build stronger operational partnerships so that evidence-based vector suppression strategies are developed and adopted more effectively.

  • The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Vector-Borne Disease Regional Centers of Excellence" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.084.
  • This funding opportunity was created on Oct 14, 2021.
  • Applicants must submit their applications by Jan 18, 2022 Electronically submitted applications must be submitted no later than 500 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $2,000,000.00 in funding.
  • The number of recipients for this funding is limited to 10 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for RFA CK 22 005

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